Adenomatoid odontogenic tumor (AOT)

  • Benign odontogenic tumor of epithelial origin.
  • Origin in enamel organ or dental lamina remnants.
  • Epithelial cells form patterns resembling glandular tumors.
  • Induction of dentinoid material.
  • Most occur in 1st and 2nd decades; very rare after age 30.
  • Most patients are females (2:1 female/male ratio).
  • Majority occur in maxilla, usually anterior.
  • 75% are pericoronal.
  • Most lesions are small (< 3.0 cm).
  • Large lesions can cause buccal-lingual expansion.
  • Usually asymptomatic.
  • Radiographic features:
    • Well-defined, often corticated radiolucency, most unilocular.
    • Completely radiolucent, but may have small radiopaque foci.
    • Pericoronal lesions often engulf most of tooth, extending apically past cemento-enamel junction (differs from dentigerous cyst).
    • Can displace teeth, resorb roots.